Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome.
“While stille experimental and off label, several studies have shown effectiveness in various medical condition,” Dr. Birken said. “It may act as an effective anti-inflammant as well as immuno-modulator for auto-immune diseases”
Also, LDN may help to decrease insulin levels which may improve growth hormone levels and increase metabolism. Some studies indicated appetite suppression as well.
“Side effects include constipation, vivid dreams, and sleep disturbances,” Dr. Birken said. “It’s best to start patients at a low dose and increase as tolerated to avoid these possible side effects.”
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