All About Skin

From Medical News Today
Prof. Hywel C. Williams, OBE, D.Sc.: a Fellow of the Academy of Medical Sciences and a National Institute for Health Research Senior Investigator Emeritus. Prof. Williams is also a professor of dermato-epidemiology and co-director of the Center of Evidence-Based Dermatology at Queen’s Medical Centre at Nottingham University Hospitals National Health Service (NHS) Trust.
Dr. Derrick Phillips: a dermatologist and spokesperson for the British Skin Foundation.
Dr. Beth G. Goldstein: Founder at Get Mr. and Central Dermatology Center.

1. Expensive skin cream can keep your skin ‘young’ forever
The skin cream industry is huge. For instance, in the United States in 2020, “prestige skin care” sales totaled $1.1 billion from April to June. And that marked an 18% drop from 2019 sales.

However, despite their lucrative popularity and regardless of cost, no skin creams can protect skin against aging indefinitely. “This is a marketing ploy and is certainly not true,” said Dr. Phillips.

As Prof. Williams explained, “Simple moisturizers can achieve quite a lot. Creams containing topical retinoids can improve photoaging effects.” He dryly notes, however, that he is “not aware of any cream that keeps skin young forever.”

Dr. Goldstein informed us that “90% of skin aging is from photodamage. So all of the creams that state they can prevent wrinkles and aging are missing the mark.”

In agreement, Dr. Phillips wrote: “The most important intervention in slowing down the process is using a sunscreen with broadband UV cover.” Notably, he also notes that “these needn’t be expensive.”

2. Drinking water keeps your skin hydrated
This is a half-truth. According to Prof. Williams, drinking water only keeps your skin hydrated “in the sense that water keeps the body hydrated and skin is the largest organ of the body.”
It is only at certain, rare times when this might be the case. “There is no evidence that drinking water directly impacts your skin unless in extremes, such as heat stroke or severe dehydration,” said Dr. Goldstein.

3. Antibacterial soap is best for the skin
This is a myth. The skin’s natural microbiome is vital for maintaining healthy skin. “Using antibacterial soaps can upset that natural balance,” explained Prof. Williams. “They can also be harsher on the skin than pH neutral soaps.”
“Removing both the good and bad bacteria on a regular basis is not always the best idea,” added Dr. Goldstein, “unless you are in a situation where this is important, for instance, if you work in healthcare, food handling, or of course, during a pandemic.”

4. Having a dirty face causes acne
In Prof. Williams’s professional opinion, this is “nonsense.” Unless, he explained, the dirt “is contamination with oily substances such as hair pomade, oily make-up, or occupational oil exposure.”
Standard dirt will not produce acne.
“Acne is caused by a complex interaction of hormones and the skin, not dirt. People will use scrubs, toners, and many products to clean their faces to address or prevent acne, but often this can just result in irritation. The pores are plugged by keratin, a protein produced by the skin cells, not dirt.”
– Dr. Goldstein
Diving into the details, Dr. Phillips said that, although the skin’s microbiome may differ in people who have acne compared with those who do not, this is not due to cleanliness.
He also adds an interesting note about a rather modern dermatological condition:
“In the past year, there has been a rise in ‘cell phone’ acne, where people get acne spots on the side of their face that presses against their mobile phones. It is thought to be related to a combination of short-wavelength visible light from smartphones, sweat, dust, heat, friction, and bacteria on the surface of the phones. Flares may be prevented by regularly cleaning phone screens.”

5. Chocolate causes acne
Simply put, Prof. Williams writes that this is “another myth.” For the reasons outlined above, this has no basis in fact.

6. All sun exposure is bad for the skin
“All sun exposure causes some degree of photodamage,” explained Prof. Williams, “but some sun exposure is essential for boosting vitamin D synthesis,” especially for people in regions that are further from the equator and those with darker skin who receive lower sun exposure.

Similarly, Dr. Philips said that “The sun is a major source of vitamin D, which is important for bone health and may play a role in the immune system. We also know that UV exposure from the sun has anti-inflammatory properties that can be beneficial in some skin conditions, such as psoriasis, eczema, and pruritus.”

However, he also explained that “[t]hese benefits must be counterbalanced against the risk of skin cancer, which we know in white populations is directly related to UV exposure.” He recommends using high-factor sunscreen, wearing appropriate clothing, and staying in the shade between 11 a.m. and 3 p.m. on sunny days.
As someone who focuses on skin cancer surgery, Dr. Goldstein took a firmer line:
“There is a skin cancer epidemic with at least five million new cancers treated each year in the U.S. The majority of these cancers are due to sun exposure.”
Although vitamin D is essential, she explained that we can also derive it from foods and supplements,“1 in 5 Americans will get skin cancer, and melanoma is set to be the most common cancer among men, and only second to breast cancer in women by 2040.”

7. A spray tan protects against UV rays
A spray tan will not protect against sun damage unless it contains added UV protectants. “Just spraying color onto the skin does not protect against UV rays,” said Prof. Williams.
Dr. Phillips reiterates the message: “They do not provide any protection against UV radiation and should not be used as an alternative to sunscreen.”

8. Vitamin E helps get rid of scars
Over the years, many scientists have investigated whether vitamin E reduces the appearance of scars, but our experts were unanimous in their responses. To date, Prof Williams says, the evidence is “unconvincing.”
Dr. Goldstein agreed that “current data do not support the use of vitamin E to help get rid of scars.”
Dr. Phillips goes one step further, writing that “in some instances, it can be detrimental.” However, as an alternative approach, he told us that “silicone gel products have been consistently shown to prevent scar overgrowth and improve the appearance of mature scars.”

9. ’Natural’ products are better for the skin
Products that are marketed as “natural” are popular among consumers. However, the term “natural” says nothing about a product’s effectiveness or safety.

“Arsenic is natural after all,” Prof. Williams reminded us. “Many natural products, such as moisturizers, are very expensive and have no additional benefit over cheaper, refined products.”

He also noted that “natural products can have just as many side effects as well-tested medical products — they may not be as effective, and they may suffer from stability issues. But it is a personal choice — if people like the sound of the word ‘natural’ as a euphemism for ‘gentle’ or ‘safe’ and want to pay for the product, that is up to them.”

“Poison ivy is all-natural,” said Dr. Goldstein, “but you would not rub it all over your skin.” She also explained that all-natural products can still have “serious environmental impacts.” Importantly, according to Dr. Phillips, natural ingredients, especially in high quantities, can trigger allergies and irritate the skin.

10. Wounds need air to heal
This is a long-standing and pervasive myth, but, as Prof. Williams explained succinctly, it is “not true — wounds heal better with a clean, moist environment.”

In agreement, Dr. Goldstein said, “Research has shown that cells migrate better to initiate and continue healing in a moist environment in the early stages of healing in particular. Keeping a wound covered with Aquaphor or similar ointment and a bandage is ideal [if there is no infection].”

She also noted that, toward the end of the healing process, once new connective tissue and microscopic blood vessels have formed, air can aid the healing process.

11. Exfoliating daily is essential for healthy skin
Skin exfoliation is the process of removing dead cells from the surface of the skin. This can be achieved by using an exfoliation tool, a granular surface, or chemicals.

Although popular, exfoliation is not essential. As Prof. Williams explained to MNT, “the skin feels smoother after exfoliating, but repeated exfoliation is damaging the natural skin barrier.”

12. Black salve is a safe treatment for skin cancer
Over recent years, so-called black salve, a derivative of the bloodroot plant, has entered the marketplace. Unscrupulous companies market it as a way to treat skin cancer. In reality, black salve can be dangerous.

Prof. Williams told us that “sanguinarine — the active ingredient in black salve — can cause severe tissue necrosis and may not kill all skin cancer cells. Always see a dermatologist to get suspected skin cancer diagnosed properly first and discuss treatment options if then confirmed.”

He also sent us a link to a recent article discussing black salve. The authors explain that “[c]linical data concerning the efficacy of bloodroot primarily come from case studies with unfavorable outcomes involving patients who self-treated with bloodroot-containing black salves.”

Dr. Goldstein mirrors these findings, explaining that “I have seen sad outcomes of people trying this treatment.” She also reiterated that black salve damages healthy tissue without effectively curing cancer.

Dr. Phillips confirms the negative consequences of black salve: “The Food and Drug Administration (FDA) has listed black salve as a fake cancer cure, and it should be avoided!”

Summary:

Skin health is essential to our well-being but patients should be aware of the many myths surrounding skin care.

Is Fish Healthier Than Red Meat?

From Medical News Today

Some people consider fish to be a healthy alternative to red meat. It is a good source of protein, omega-3 and omega-6 fatty acids, and several minerals and vitamins.

 

Omega-3 fatty acids, which, as research has shown, can have a positive effect on heart health, are present in high concentrations in oily fish, such as salmon and mackerel.

 

Research indicates these fatty acids can also promote greater blood flow to the brain, which is vital for delivering oxygen essential for brain function. And one study has suggested that omega-3s may have a role in healthy brain aging.

 

Eating fish may also combat inflammation: a recent study found that regular consumption of fish helped reduce the incidence of chronic inflammatory conditions and may even benefit the immune system.

 

But not all fish are equal. “Cold-water fish have a higher amount of fat to keep the fish warm in icy waters, but this also loads the fish with beneficial omega-3 and omega-6 fatty acids,” said Kate Cohen, MS, RDN, for the Ellison Clinic at Providence Saint John’s Health Center in Santa Monica, CA.

 

Is wild-caught fish sustainable?

Shocking images of waste, environmental pollution, and bycatch (catching a species of fish or marine species unintentionally), including marine mammals, turtles, and seabirds, have led many to question whether the health benefits of fish and seafood are worth the environmental costs.

 

The Marine Stewardship Council (MSC) sets the standard for sustainable fisheries worldwide, with organizations such as Monterey Bay Aquarium Seafood Watch fulfilling a similar role in the United States. The MSC refutes the claim that there is no such thing as sustainable fishing, outlining three principles for sustainable fisheries: sustainable fish stocks, minimizing environmental impacts, and effective fisheries management.

 

If wild fish stocks cannot supply the amount of fish needed for optimal intake of fatty acids, where can the fish originate?

 

An obvious alternative to wild-caught fish is fish farming, or aquaculture. There are no issues with bycatch, the fish is cheaper to buy, supply is more reliable, and there is less effect on wild habitats. But is farmed fish as good for us as wild-caught fish?

 

“It really comes down to what the fish eats and its environment,” said Cohen . “Farmed salmon, for example, can have about 40% more calories than wild salmon and about 50% more fat — which is a pretty huge difference.”

 

So, should we eat fish? The nutrients in fish are important, but it is possible to get them elsewhere if you are concerned about sustainability issues.

 

And the key to a healthy lifestyle is ensuring that your diet is varied.  Cohen stressed that it is not just about eating fish: “Research has shown that diets that incorporate these healthy fats — like the Mediterranean Diet — are associated with positive health outcomes. Aim for a whole-food diet whenever possible.”

 

The message, therefore, is that if you want to eat fish, read the label carefully to ensure it is from a sustainable source and choose cold-water oily fish for the greatest health benefits as part of a balanced and varied diet.

What Does It Mean to Be Physically Fit?

From Medical News Today

Being physically fit depends on how well a person fulfills each of the components of being healthy.

 

When it comes to fitness, these components are:

 

Cardiorespiratory fitness

Muscular strength

Muscular endurance

Body composition

Flexibility

 

Cardiorespiratory performance

Cardiorespiratory endurance indicates how well the body can supply fuel during physical activity via the body’s circulatory and respiratory systems.

 

Activities that help improve cardiorespiratory endurance are those that cause an elevated heart rate for a sustained period of time.

 

These activities include:

Swimming

Brisk walking

Jogging

Cycling

People who regularly engage in these activities are more likely to be physically fit in terms of cardiorespiratory endurance. It is important to begin these activities slowly and gradually increase the intensity over time.

 

Exercising increases cardiorespiratory endurance in a number of ways. For example, the heart muscle becomes stronger so that it is able to pump more blood per heartbeat.

 

At the same time, additional small arteries grow within muscle tissue so that they can deliver blood to working muscles more effectively when needed.

Cardiorespiratory fitness can help reduce the risk of conditions including:

Heart disease

Type 2 diabetes

Stroke

 

Muscular strength

There are a number of ways to measure muscular strength. Generally, lifting a set weight in a prescribed position and comparing the results against any given population is the best way.

 

In general, if a person works their muscles consistently and regularly, they will increase in strength.

There are various ways of putting the muscles through rigorous activity, but anything that works a muscle until it is tired will increase muscle strength over time.

 

How does muscle structure change with exercise?

Muscles consist of elongated muscle cells. Each muscle cell contains contractile proteins, called actin and myosin, that give the muscle its strength.

 

These fibers contract together, producing the so-called power stroke. The total force depends on the number of these units contracting in unison.

 

To build muscle, an individual must regularly exercise their muscles and take in enough protein.

 

Scientists do not fully understand the exact mechanism of muscle building, but the general principles are well known. Training causes the muscle cells to expand, and there is an increase in actin and myosin production.

 

Muscular endurance

Fitness can also include muscular endurance, which is the ability of a muscle to continue exerting force without tiring.

 

As mentioned above, strength training builds bigger muscles. Endurance training, on the other hand, does not necessarily generate muscles of a larger size.

 

This is because the body focuses more on the cardiovascular system, ensuring that the muscles receive the oxygenated blood they need to keep functioning.

 

Another important change in muscles that people specifically train for endurance concerns the different types of muscle tissue: fast twitch and slow twitch fibers.

 

Fast twitch fibers contract quickly but get tired quickly. They use a lot of energy and are useful for sprints. They are whitish, as they do not require blood to function.

 

Slow twitch fibers are best for endurance work, as they can carry out tasks without getting tired. They are present in core muscles. These fibers appear red, as they rely on a good supply of oxygenated blood and contain stores of myoglobin.

 

Different exercises will promote fast twitch fibers, slow twitch fibers, or both. For example, a sprinter will have comparatively more fast twitch fibers, whereas a long distance runner will have more slow twitch fibers.

 

Body composition

Body composition measures the relative amounts of muscle, bone, water, and fat an individual has.

 

A person can potentially maintain the same weight but radically change the ratio of each of the components that make up their body.

 

For instance, people with a high muscle (lean mass) ratio might weigh more than those with the same height and waist circumference who have less muscle.

 

Flexibility

Flexibility refers to the range of movement across a joint.

 

Flexibility is important because it improves the ability to link movements together smoothly and can help prevent injuries. It is specific to each joint and depends on a number of variables, including the tightness of ligaments and tendons.

 

Various activities that stretch the joints, ligaments, and tendons can increase flexibility.

 

There are three common types of stretches that people use to increase flexibility:

 

Dynamic stretching: This refers to the ability to complete a full range of motion in a particular joint. People use this type of stretch in standard warmup exercises, as it helps prepare the body for physical activity.

Static-active stretching: This refers to holding the body or part of the body in a stretched position and maintaining that position for a period of time. One example of static-active stretching is the splits.

Ballistic stretching: People should only engage in ballistic stretching when the body is already warmed up and limber from exercise. It involves stretching in various positions and bouncing.

There are a number of ways to improve flexibility. Having a daily stretching regimen can be the simplest and most efficient way of achieving whole body flexibility.

 

Summary

In general, fitness means different things to different people.

 

The important message is that embarking on any regular exercise will be of benefit to a person’s health. The more exercise they do, the healthier they will look and feel.

 

Flavonoid-Rich Food and Drinks May Lower Blood Pressure

From Medical News Today

Dietary advice from healthcare professionals can seem joyless, typically requiring people to stay away from a list of treats that scientists have found to be “bad” for health.

 

Major exceptions to this rule are flavonoid-rich foods and drinks, which include dark chocolate, blueberries, and strawberries.

 

Research indicates that flavonoids may protect against:

 

high blood pressure

heart attack and stroke

type 2 diabetes

certain types of cancer

A new study now suggests that the bacteria that live in our gut, known as the gut microbiota, may be partly responsible for the beneficial effect of dietary flavonoids on blood pressure.

 

High blood pressure is a major risk factor for cardiovascular disease, which is the leading cause of death in the United States.

 

Researchers at Queen’s University Belfast in Northern Ireland, United Kingdom, recently led a study that found that individuals who consumed the most flavonoid-rich foods tended to have lower blood pressure.

 

The diversity of participants’ gut microbiota accounted for a significant portion of the association between flavonoids and blood pressure.

 

Specifically, the scientists’ analysis found that eating 1.6 servings of berries a day — where one serving equals 1 cup or 80 grams of berries — was associated with an average reduction of 4.1 millimeters of mercury (mm Hg) in systolic blood pressure.

 

Systolic blood pressure is the pressure in a person’s arteries when their heart contracts, whereas diastolic blood pressure is the pressure when the heart relaxes. In a blood pressure reading, the first number is the systolic blood pressure, and the second is the diastolic value.

 

A healthy blood pressure is usually less than 120/80 mm, whereas high blood pressure is typically 140/90 mm or above.

 

The diversity and composition of the gut microbiota explained about 11.6% of the association between berry consumption and blood pressure.

 

Similarly, drinking 2.8 glasses of red wine a week (125 milliliters per glass) was associated with a 3.7-mm Hg reduction in systolic blood pressure. The gut microbiota accounted for 15.2% of this association.

 

“Eating 1.5 servings of berries a day resulted in clinically relevant reductions in systolic blood pressure,” said lead author Aedín Cassidy, Ph.D., chair and professor in nutrition and preventive medicine at the Institute for Global Food Security at Queen’s University.

 

Professor Cassidy believes that a class of flavonoids called anthocyanins appears to be key to this effect.

 

Anthocyanins are the pigment molecules responsible for the red or blue color of many fruits, including red grapes, blueberries, blackcurrants, and blackberries.

 

Previous research has found that gut bacteria break down flavonoids into compounds that have more powerful protective effects on the heart.

 

Conversely, regular consumption of flavonoid-rich foods also influences the composition of the gut microbiota.

 

“A better understanding of the highly individual variability of flavonoid metabolism could very well explain why some people have greater cardiovascular protection benefits from flavonoid-rich foods than others,” says Prof. Cassidy in a press release on the study.

 

Highlights from Recent European Journal for Breast Health on Lower Risk for Breast Cancer with Hormone Pellets

Highlights from Recent European Journal for Breast Health on Lower Risk for Breast Cancer with Hormone Pellets

Objective: Testosterone (T) therapy has been shown to be breast protective in both pre- and post-menopausal patients. Additionally, estradiol (E) does not cause breast cancer (BC) in the majority of the world’s literatures. This study aimed to investigate the incidence of invasive BC (IBC) in pre- and postmenopausal women treated with T therapy and T in combination with E (T/E).

Materials and Methods: Since January 2010, a total of 2,377 pre- and post-menopausal women were treated with T or T/E implants. IBC rates were reported based on newly diagnosed IBC cases in the total study. Total cases divided by the total sample size and years in study was expressed as an incidence per 100,000 person-years (P-Ys). The BC incidence was compared with age-specific Surveillance Epidemiology and End Results (SEER) incidence rates.

Results: As of October 2020, 14 cases diagnosed with IBC have been found in 9,746 P-Y of follow up for an incidence of 144 cases per 100,000 P-Y, substantially less than the age-specific SEER incidence rates (223/100,000), placebo arm of Women’s Health Initiative Study (330/100,000), and never users of hormone therapy from the Million Women Study (312/100,000).

Conclusion: T and/or T/E pellet implants significantly reduced the incidence of BC in pre- and post-menopausal women. The addition of E did not increase the incidence over using T alone. This is the second multi-year long-term study demonstrating the benefits of T therapy in reducing the incidenceof IBC.

Key Points

• In the United States, 240,000 women will develop breast cancer (BC) annually and 40,000 will die from the disease.

• Testosterone hormone optimization has been shown to reduce the incidence of invasive breast cancer in women.

• This study (The Testosterone Therapy and Breast Cancer Incidence Study) is the largest long-term study to further demonstrate this benefit and shows a reduced incidence of IBC in women taking testosterone and estradiol sub-cutaneous hormone pellet therapy