Medical Myths About Irritable Bowel Syndrome

From Medical News Today

  1. We know what causes IBS

Dr. Farhadi told Medical News Today that although research is uncovering more about IBS, we still do not know what causes it.

 

While certain foods such as dairy products or spicy foods may trigger symptoms, they do not cause the condition.

 

He noted, however, that post-infectious IBS can be caused by bacteria such as Campylobacter jejuni.

 

  1. Stress causes IBS

In recent years, research has suggested that levels of mental stress influence gut bacteria composition and play a key role in IBS via the gut-brain axis.

 

Dr. Farhadi says, however, that people with and without IBS generally face similar amounts of stress, meaning that it may be how people manage stress — rather than stress alone — that influences whether or not they may experience IBS symptoms.

 

“In my book on IBS, [I wrote about a study showing] that when a person is stressed, numbers of mast cells in their gut increase. So stress doesn’t just increase the release of hormones and mediators in the gut; it also changes the anatomy of the gut in a way that makes it more sensitive to stress,” he explained.

 

“This means that even if you come out of that stressful period, your gut is not the same gut you had before. IBS symptoms triggered by stress can thus linger even though the stress is gone. And this is very common in patients with IBS,” he added.

 

Dr. Farhadi also mentioned a study he conducted that found that subjective perception of well-being is linked to fewer symptoms of IBS.

 

Previous research has also suggested that psychological, social, and genetic factors may all play a role in the development of IBS symptoms.

 

  1. Doctors only diagnose IBS via ‘fancy tests’

“IBS can be diagnosed without fancy tests,” Dr. Farhadi told us. “With the right clinical criteria, doctors can diagnose IBS with 97% accuracy in 5 years. No other test in the medical field has that kind of accuracy.”

 

“We diagnose IBS based on the Rome IV criteria: Patients with IBS should report symptoms of abdominal pain at least once weekly — on average — in association with a change in stool frequency, a change in stool form, and/or relief or worsening of abdominal pain related to defecation,” explained Dr. Jackson.

 

“There are subtypes of IBS, and you may have predominantly diarrhea, constipation, or a mixed pattern. Patients often also experience bloating, but his symptom is not needed in making the diagnosis,” she added.

 

  1. IBS is curable

There are different ways of treating IBS, including a mixture of prescription medication and lifestyle changes tailored to each person’s individual situation.

 

“I can assure you in the overwhelming majority of cases, management is very cheap and simple: fiber, probiotics, reassurance, and exercise,” said Dr. Farhadi.

 

When it comes to medication, according to Dr. Farhadi, it can be a “trial and error” experience. However, it can help relieve the symptoms caused by IBS, alongside other interventions.

 

“Ultimately, there is no cure for IBS,” Dr. Farhadi noted, and sometimes medication may “only [work] like a band aid for symptom relief. I have to repeat prescriptions for medications like management of bacterial overgrowth with antibiotics. Ultimately, there is no cure for IBS.”

 

  1. IBS is uncommon, does not affect quality of life

“IBS is often a chronic, debilitating, and common disorder of the gut-brain interaction,” said Dr. Jackson.

 

Its “prevalence in North America is 10-15% and is associated with increased health care costs,” she emphasized, adding that “[I]t can significantly affect patients’ quality of life.”

 

“One study highlighted the negative impact of IBS with patients reporting that they would give up 10–15 years of their life expectancy for an instant cure for their condition.”

 

  1. All types of exercise help IBS

While Dr. Farhadi agreed that some kinds of exercise do help IBS, he said that not all exercise is the same.

 

“Competitive exercise doesn’t relieve stress — it produces stress. The same is true for weight-lifting in the gym if you have to pay a lot of attention to what kind of weight you’re lifting, how you’re pulling this muscle, and how you’re pushing that muscle,” he noted.

 

He also said that many runners have what is known as “runner’s run,” or diarrhea after running for long periods. Thus, he warned, it is very likely that long periods of running can cause IBS symptoms to flare.

 

  1. Meditation helps

While some studies suggest that meditation may help relieve symptoms of IBS, research is ongoing.

 

“We are continuing to understand the brain-gut-microbiome axis and how it plays a role in IBS,” said Dr. Jackson. “Gut-directed psychotherapies have been shown to be beneficial in improving IBS symptoms.”

 

“Meditation and mindfulness have shown to help stimulate changes in the brain and how we process thoughts, sensations, and emotional responses, and this may positively affect how we perceive and interpret signals from the gut, thus improving IBS symptoms,” she added.

 

That said, different kinds of meditation may work differently for different people. While it may not work for everyone, Dr. Farhadi recommends “mindless meditation,” which includes walking for 30 minutes per day on the same route until it gets so boring that one stops paying attention to their surroundings.

 

“That’s a meditative walk — you do meditation and walk together. It’s a stress reliever to reboot your system. But it needs a lot of practice. After 1 year, you may get into that zone for 1 minute out of the 15 you’re trying to do,” he said.

 

  1. Cutting out lactose helps

A recent review found that, although many patients with IBS report milk intolerance, there is no conclusive link between IBS and lactose intolerance.

 

As around two-thirds of the world’s population is lactose intolerant, it is reasonably likely for someone to be lactose intolerant and have IBS. This means that cutting out dairy products may help relieve gastrointestinal symptoms.

 

“Many patients with IBS associate their symptoms with eating and try to ease their symptoms by avoiding certain foods,” said Dr. Jackson. “An elimination diet involves removing multiple foods out of your daily diet and then slowly reintroducing them to help identify trigger foods.”

 

“The most studied diet for IBS is the low FODMAP diet. FODMAP foods can lead to increased gas and distension and the triggering of meal-related symptoms in patients with IBS. Dairy is a high FODMAP food, and for some/many may be a dietary trigger, but this is not universally true,” she explained.

 

“Food choices can be overwhelming and if available, a gastrointestinal dietician can help guide you in this process,” she added.

 

  1. Natural treatments work for IBS

Natural remedies such as peppermint oil and cardamom have shown some promise in relieving symptoms of IBS and gastric ulcers. However, research into natural remedies is limited, so they may not be universally helpful.

 

“Black cardamom seeds and spearmint are muscle relaxants for the gut, and so they could reduce symptoms,” said Dr. Farhadi.

 

“People can try these natural remedies and others as long as they are not really strong chemicals. Many herbal remedies have been around for thousands of years, and people are using them with no problem,” he added.

 

Nevertheless, it is always recommended to check with a doctor before taking on any new line of treatment.

 

  1. Fasting relieves IBS

“Imagine you have an engine, and the engine has a problem. Now you turn it off. Or course, you may not have any problems as long as it’s off, but how long can you keep it off?” said Dr. Farhadi.

 

“So, if you reduce the number of times you eat from perhaps three to two times per day, you may reduce the number of symptoms you experience per day. It may help, but it isn’t necessarily the way to go,” he explained.

 

“Fasting, however, is good for other things — such as weight loss and memory,” he added.

 

  1. Fiber helps IBS

If a patient has chronic constipation, Dr. Farhadi said that fiber could help. However, if overdone, fiber can lead to bloating from excess gas in the gut.

 

To avoid this, Dr. Farhadi recommended consuming fiber via a pinch of water-soluble fiber psyllium — a prebiotic — on a spoon of Greek yogurt, which is a probiotic.

 

  1. There is an IBS diet

“There’s no specific diet for IBS,” said Dr. Farhadi.

 

“Diets are not only individualized; they are dynamic. One person may be able to drink coffee when on vacation yet experiences problems with it during finals. As there is no specific diet for different individuals, there is no specific diet for individuals at all times,” he advised.

 

Omega -3 Fats – What they Can and Can’t Do For Health

Omega-3 fats: What they can do for health

Decades of research on the health impacts of omega-3 fatty acids have provided controversial findings. Here are some evidence-backed benefits of consuming omega-3 fatty acids.

Anti-inflammatory properties

Chronic inflammation — also called low-grade inflammation — is linked to the development of obesityT, heart disease, and cancers.

Omega-3 fatty acids have been shown to exert anti-inflammatory effects in the human body and may aid in lowering markers of inflammation, such as C-reactive protein and interleukin-6.

In fact, omega-3 fatty acids are regarded as one of the most potent lipids capable of reducing oxidative stress and inflammation. It also potentially guards against the development of chronic diseases.

 

Lower cholesterol

In a 6-week study, daily supplementation with at least 1.2 g of DHA significantly reduced triglyceride levels and increased “good” cholesterol, or high-density lipoprotein.

In addition, omega-3 fatty acids lowered the “bad” cholesterol, low-density lipoproteins (LDL), when dietary saturated fats were replaced with polyunsaturated and monounsaturated fatty acids found in plants foods such as nuts and avocados.

Elevated triglycerides and LDL cholesterol are linked to an increased risk for metabolic syndrome and heart disease.

However, a recent evidence-based practice summary has shown no impact on a range of cardiovascular disease (CVD) outcomes from the use of omega-3 fatty acid supplements in patients with established CVD or raised risk factors for CVD.

 

Lower blood pressure

On the other hand, omega-3 fatty acids have been shown to improve vascular health — the health of the blood vessels — by increasing the bioavailability of nitric oxide.

In a phase 2 scientific study, nitric oxide induced dilation (relaxation) of the blood vessels and led to a significant reduction in blood pressure.

 

May reduce the risk of heart disease

By reducing markers associated with an increased risk of developing heart disease — high triglycerides, cholesterol, and blood pressure — omega-3 fatty acids may reduce the risk of heart disease, according to a review analyzing existing studies.

The same review concluded that high-dose daily supplementation with 4 g of purified EPA in people with elevated triglycerides levels led to a 25% reduction in cardiovascular events.

In their 2018 review, Prof. Fereidoon Shahidi, professor of biochemistry at Memorial University, Canada, and Prof. Priyatharini Ambigaipalan, currently at the School of Science and Engineering Technology at Durham College, also in Canada, identified evidence of health benefits from omega-3 in noncardiovascular health conditions.

 

Improve tolerance to cancer treatment

Omega-3 fatty acids may improve the efficacy and tolerance of chemotherapy and is a potential supportive treatment to people undergoing cancer treatment.

More specifically, daily supplementation with EPA and DHA helped patients with head and neck cancers and breast cancer to maintain body weight and reduce cancer-related muscle loss.

 

Improves depression

A 2019 review study of over 2,000 participants showed a beneficial impact of EPA omega-3 fatty acids on depression, with DHA showing little benefits.

This finding is supported by other studies included in Prof. Shahidi’s and Prof. Ambigaipalan’s review, indicating that fish oil supplementation helps protect against major depressive disorder in people between the ages of 15 and 25 years.

Furthermore, moderate intakes of fatty fish and seafood were associated with fewer occurrences of depression.

 

Omega-3 fats: What they cannot do for health

Omega-3 fatty acids have been successfully marketed as heart-friendly and reported to reduce the risk of adverse heart disease-related outcomes.

However, its role and health benefits for some conditions have been challenged and discredited. This Cochrane report review found no evidence of the benefit of omega-3 supplements on heart disease, stroke, or death.

Here are some conditions that omega-3 fatty acids may not prevent or improve, based on the latest scientific evidence.

 

Reduce risk of death by heart disease

Prof. Shahidi and Prof. Ambigaipalan also found that the consumption of omega-3 fatty acids does not reduce the risk of adverse heart disease-related outcomes, such as sudden cardiac death, heart attack, or stroke, even in individuals without a history of disease.

Although omega-3 fats lower the risk of developing heart disease by lowering triglyceride, the “bad” cholesterol LDL, and blood pressure, a meta-analysis of over 80,000 individuals found that their supplementation neither prevented death from all causes nor heart disease.

 

Prevent blood clots

Anti-clotting effects of omega-3 fatty acids have been proposed by reducing platelet aggregation. However, this finding has been controversial, and the evidence in this regard is weak — typical doses of omega-3 fats from foods and supplements have a mild effect.

 

Prevent or treat diabetes

Evidence suggests that increasing omega-3 intake does not prevent or treat diabetes.

It does not affect fasting blood sugar, insulin resistance, or glycosylated hemoglobin in those with type 2 diabetes and metabolic syndrome.

 

Prevent cancer

Omega-3 fatty acids have been reported to reduce the complications of some cancer patients, and early findings look promising. However, there is no evidence of any action of omega-3s preventing the development of cancers.

In a meta-analysis of over one million people, a particularly high intake of omega-3 fats — 5–15 g per day — did not significantly reduce lung cancer risk, and in some cases, increased the risk of developing lung cancer.

Therefore, too low or too high omega-3 intake may be harmful.

 

The bottom line

Omega-3 polyunsaturated fatty acids are essential compounds that are key building blocks for cell membranes, particularly in the brain.

For decades, they have been the subject of scientific interest, but findings have been controversial and inconsistent.

The evidence shows that omega-3 fatty acids have anti-inflammatory properties and may lower cholesterol, blood pressure, depressive episodes, weight loss during cancer treatment, and the risk for heart disease.

However, omega-3 intake does not reduce the risk of adverse and severe heart disease-related outcomes, including sudden death and stroke. Additionally, it cannot prevent or treat diabetes or prevent blood clots.

This is an emerging area of evidence, and further results will continue to inform health recommendations.

Medical Myths about Dementia

From Medical News Today

  1. Dementia is inevitable with age

This statement is not true. Dementia is not a normal part of aging.

According to a report that the Alzheimer’s Association published, Alzheimer’s disease, which is the most common form of dementia, affects 3% of people aged 65–74 years in the U.S.

As a result of the risk increasing as we age, 17% of people aged 75–84 years and 32% of people aged 85 years and older have a dementia diagnosis.

 

  1. Dementia and Alzheimer’s disease are the same thing

This is not quite correct. Alzheimer’s is a type of dementia, accounting for 60–80% of all dementia cases. Other types of dementia include frontotemporal dementia (FTD), vascular dementia, mixed dementia, and Lewy body dementia.

The National Institute on Aging define dementia as “the loss of cognitive functioning — thinking, remembering, and reasoning — and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.”

Although dementias share certain characteristics, each type has a distinct underlying pathology.

Alzheimer’s disease is associated with a buildup of so-called plaques and tangles in the brain. These structures interfere with brain cells, eventually killing them. In contrast, brain cell death in vascular dementia occurs due to a lack of oxygen, which can result from a stroke, for instance.

FTD, as another example, occurs when abnormal protein structures form in the frontal and temporal lobes of the brain, causing the brain cells in these regions to die.

 

  1. A family member has dementia, so I will get it

A common myth is that dementia is purely genetic. In other words, if a person’s family member has a dementia diagnosis, they are guaranteed to develop dementia later in life. This is not true.

Although there is a genetic component to some forms of dementia, the majority of cases do not have a strong genetic link.

As we learned above, rather than genetic factors, the most significant risk factor for dementia is age. However, if a parent or grandparent developed Alzheimer’s when they were younger than 65 years, the chance of it passing on genetically is higher.

Early-onset Alzheimer’s is relatively uncommon, though. It occurs in about 5.5% of all Alzheimer’s cases.

As the majority of dementia cases are Alzheimer’s disease, this means that most dementia cases are not hereditary. FTD, which is much less common, has a stronger genetic link, but if a parent or grandparent develops the condition, it does not mean that children or grandchildren are guaranteed to develop it.

 

Today, FTD affects an estimated 15–22 in every 100,000 people. Of these individuals, 10–15% have a strong family history of the condition.

 

  1. Dementia only affects older adults

Age is a risk factor for dementia, but dementia can affect younger adults in rare cases. Some scientists estimate that, in people aged 30–64 years, 38–260 people in 100,000 — equivalent to 0.038–0.26% — develop early-onset dementia.

In the 55–64 age bracket, this increases to close to 420 people in 100,000, or 0.4%.

 

  1. Using aluminum pans causes Alzheimer’s

In the 1960s, scientists injected rabbits with high levels of aluminum. They found that the animals developed neurological lesions similar to those that form in the brains of people with Alzheimer’s.

Additionally, some studies have identified aluminum within the plaques associated with Alzheimer’s. However, aluminum also appears in the healthy brain, and researchers have not established a causal link between this element and the disease.

Following on from these studies, myths still circulate that drinking from aluminum cans or cooking with aluminum pots increases the risk of Alzheimer’s.

However, since those early experiments, scientists have not found a clear association between Alzheimer’s and using aluminum pots and pans.

Although researchers will, eventually, establish the precise relationship between aluminum and Alzheimer’s, consuming aluminum through the diet is unlikely to play a major role.

As the Alzheimer’s Society explain: “Aluminum in food and drink is in a form that is not easily absorbed into the body. Hence, the amount taken up is less than 1% of the amount present in food and drink. Most of the aluminum taken into the body is cleaned out by the kidneys.”

However, they also write that some research has found “a potential role for high dose aluminum in drinking water in progressing Alzheimer’s disease for people who already have the disease.”

 

  1. Dementia signals the end of a meaningful life

Thankfully, this is not the case. Many people with a dementia diagnosis lead active, meaningful lives. Some people fear that if a doctor diagnoses them with dementia, they will no longer be able to go for a walk alone and will have to stop driving their vehicle immediately.

It is true that these adjustments may come in time as the condition progresses, but in mild cases of dementia, no changes may be necessary. As dementia worsens, changes to the way an individual leads their life are likely, but that does not mean that the person cannot lead a fulfilling life.\“Too many people are in the dark about dementia — many feel that a dementia diagnosis means someone is immediately incapable of living a normal life, while myths and misunderstandings continue to contribute to the stigma and isolation that many people will feel,” explains Jeremy Hughes, former Chief Executive of the Alzheimer’s Society.

“[W]e want to reassure people that life doesn’t end when dementia begins.”

– Jeremy Hughes

 

  1. Memory loss always signifies dementia

Although memory loss can be an early symptom of dementia, it does not necessarily signify the start of this condition. Human memory can be unpredictable, and we all forget things occasionally. However, if memory loss is interfering with everyday life, it is best to speak with a doctor.

Although memory issues tend to be an early sign of Alzheimer’s disease, that is not the case for other forms of dementia. For instance, early signs and symptoms of FTD can include changes in mood and personality, language difficulties, and obsessive behavior.

 

  1. Dementia is always preventable

This, unfortunately, is untrue. Importantly, though, certain factors can either reduce the risk of certain types of dementia developing or delay their onset.

For instance, the Lancet Commission’s 2020 report on dementia prevention, intervention, and care lists 12 factors that increase the risk of dementia:

 

Less education

Hypertension

Hearing impairment

Smoking

Obesity

Depression

Physical inactivity

Diabetes

Low levels of social contact

Alcohol consumption

Traumatic brain injury

Air pollution

Some of these factors are more difficult to modify than others but working on changing any of them might help reduce the risk of developing dementia. The authors of the report explain:

“Together, the 12 modifiable risk factors account for around 40% of worldwide dementias, which consequently could theoretically be prevented or delayed.”

However, as Dr. Nancy Sicotte, a neurologist at Cedars-Sinai hospital in Los Angeles, CA, explains, “Reducing your risk requires starting these lifestyle changes from the get-go, not waiting until you’re 70.”

 

  1. Vitamins and supplements can prevent dementia

Linked to the section above, this is also false. To date, there is no strong evidence that any vitamin or mineral supplements can reduce the risk of dementia. In 2018, the Cochrane Library conducted a review with the aim of answering this question.

Their analysis included data from more than 83,000 participants across the 28 included studies. Although the authors report “some general limitations of the evidence,” they conclude:

“We did not find evidence that any vitamin or mineral supplementation strategy for cognitively healthy adults in mid or late life has a meaningful effect on cognitive decline or dementia, although the evidence does not permit definitive conclusions.”

 

  1. All people with dementia become aggressive

In some cases, people with dementia might find it increasingly hard to make sense of the world around them. This confusion can be frustrating, and some individuals might respond to the emotions in an angry manner. However, this is not the case for everyone.

In a study involving 215 people with dementia, 41% of the participants developed aggression during the 2-year study. When they looked at factors that increased the risk of developing aggression, the researchers identified two of the primary factors as physical pain and a low-quality relationship between the person and their caregiver.

 

  1. Dementia is never fatal

Unfortunately, dementia can be fatal. According to a 2020 study among adults aged 70-99 years, dementia may be a more common cause of death than experts have traditionally thought. The authors “found that approximately 13.6% of deaths were attributable to dementia over the period 2000–2009.”

Dementia worries people, especially as they age, and this is justifiable in many ways. However, it is important to counter misinformation that might enhance concerns and stigma.

 

  1. Low Levels of Testosterone is Found in Patients with Dementia

 

Studies have confirmed that testosterone levels are associated with cognitive impairment and that testosterone supplementation has obvious neuroprotective effects. Most clinical studies have also supported the association between low testosterone levels and cognitive impairment

 

  1. Conclusion

For now, researchers are working tirelessly to develop better ways to treat and prevent dementia. In the future, hopefully, science will reduce the impact of dementia and, therefore, the fear associated with the condition.